
Weight Management
The U.S. and global prevalence of obesity has been rising steadily in the past decades. Obesity and higher weights are associated with various health complications, including type 2 diabetes, cardiovascular disease, stroke, certain cancers, obstructive sleep apnea syndrome (OSAS), non-alcoholic fatty liver disease (NAFLD), and musculoskeletal disorders.
Weight management to address overweight and obesity involves implementing strategies for achieving and maintaining a healthy weight while recognizing that bodies come in all shapes and sizes. It involves adopting balanced eating habits, engaging in regular physical activity, and prioritizing overall well-being. Factors such as genetics, cultural background, mental health, and socioeconomic status play a role in a person’s relationship with food and body image (1).
Individuals with higher weight or obesity can also benefit from incorporating supplements that support metabolic health, along with a balanced diet and regular physical activity.
About the Protocol
Whey Protein- Perfect Protein Whey
Recommended Dose: 30-60grams/day (2-3)
Perfect Protein® Whey supports a healthy, active lifestyle with a complete protein source.
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Combines whey isolate and hydrolyzed whey protein for easy digestion
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Delivers 20 grams of high-quality protein per serving
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Supports overall health, energy levels, metabolism, and muscle tissue
Omega-3 fatty acids (EPA/DHA)- Super EPA
Recommended Dose: 400–2,040 mg (as 180–600 mg EPA/120–1,620 mg DHA), 1–3 times per day, for 4–12 weeks
Thorne’s Super EPA provides the highest quality, purest fish oil available from sustainably-sourced, cold-water fish.
Super EPA contains two vital omega-3 fatty acids – EPA and DHA – important throughout adulthood, as well as during periods of increased brain growth that characterize prenatal and postnatal development.
Benefits of Super EPA
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Support for a healthy cardiovascular system – supports the health of blood vessels to promote optimal blood flow and helps maintain already normal triglyceride and cholesterol levels
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Promotes a healthy inflammatory response in joints and muscles
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Supports immune function
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Nutritional support for development and maintenance of healthy brain function
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Supports memory and mood
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Promotes healthy skin
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Helpful for weight management by promoting a healthy insulin response
Probiotics- GLP-1 Probiotic Pro
Recommended Dose: ≥10 billion CFUs per day of a single- or multi-strain probiotic for a minimum of 8 weeks (4)
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Akkermansia muciniphila generates the postbiotics propionate and p9 which supports GLP-1 production.
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Clostridium butyricum produces the postbiotic butyrate which stimulates GLP-1.
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Bifidobacterium infantis produces the postbiotics acetate and lactate which feed bacteria such as Akkermansia and Butyricum, promoting an ecosystem in the gut that supports a healthy gut lining and GLP-1 naturally.
Benefit of Probiotics:
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Research shows that probiotics had a significant effect on reducing body weight, BMI, waist circumference, fat mass, insulin, total cholesterol, and low-density lipoprotein (LDL) compared to the groups not given probiotics. (4)
EGCG (Epigallocatechin Gallate)
Recommended Dose: 500–800 mg per day for 12 weeks (5)
EGCg (epigallocatechin gallate) is a key active component of green tea (Camellia sinensis) leaves. It is valued for its antioxidant properties and has been studied extensively for weight loss through promotion of fat metabolism and for its role in supporting overall health and wellness. This formula contains green tea standardized to 45% EGCg.
Benefit of EGCG:
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≥800 mg per day of green tea extract for <12 weeks or <500 mg per day of green tea for 12 weeks decreased waist circumference in participants with obesity. 5
Fiber- Fiber Prebiotic Complete
Recommended Dose: 5–20 g per day for 12–16 weeks (6-7)
Fiber Prebiotic Complete is the ultimate fiber product to promote digestive health and support those with occasional diarrhea and constipation. It is a synergistic blend of soluble and insoluble fibers. Unlike many fiber supplements, this product is free from grain-based or legume-based fibers, making it a great option for individuals with specific dietary sensitivities.
Benefits of Fiber Prebiotic
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Supportive role in healthy glucose and fat metabolism,
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Normalize appetite
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Potentially healthy body composition
Conjugated Linoleic Acid (CLA) 1000mg
Recommended Dose: 3–4.5 g per day for 4–12 weeks (8-9)
Conjugated linoleic acid (CLA) is a dietary supplement formulated to help aid body composition and support weight control.
Several studies explore possible benefits of CLA to include the possibility of maintaining healthy fat disposition, moderate energy innate and maintaining a healthy metabolic rate.
References
1. Office of Dietary Supplements – Dietary supplements for weight loss. (2022, May). https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/ 2. Sepandi, M., Samadi, M., Shirvani, H., Alimohamadi, Y., Taghdir, M., Goudarzi, F., & Akbarzadeh, I. (2022). Effect of whey protein supplementation on weight and body composition indicators: A meta-analysis of randomized clinical trials. Clinical Nutrition ESPEN, 50, 74–83. 3. Badely, M., Sepandi, M., Samadi, M., & Parastouei, K. (2019). The effect of whey protein on the components of metabolic syndrome in overweight and obese individuals; a systematic review and meta-analysis. Diabetes & Metabolic Syndrome (Print), 13(6), 3121–3131. 4. Da Silva Pontes, K. S., Guedes, M. R., Cunha, M. R., De Souza Mattos, S., Silva, M. I. B., Neves, M. F., Marques, B. C. a. A., & Klein, M. R. S. T. (2021). Effects of probiotics on body adiposity and cardiovascular risk markers in individuals with overweight and obesity: A systematic review and meta-analysis of randomized controlled trials. Clinical Nutrition, 40(8), 4915–4931. 5. Lin, Y., Shi, D., Su, B., Wei, J., Găman, M., Macit, M. S., Nascimento, I. J. B. D., & Guimarães, N. S. (2020). The effect of green tea supplementation on obesity: A systematic review and dose–response meta‐analysis of randomized controlled trials. Phytotherapy Research, 34(10), 2459–2470. 6. Huwiler, V. V., Schönenberger, K. A., Von Brunegg, A. S., Reber, E., Mühlebach, S., Stanga, Z., & Balmer, M. L. (2022). Prolonged Isolated Soluble Dietary Fibre Supplementation in Overweight and Obese Patients: A Systematic Review with Meta-Analysis of Randomised Controlled Trials. Nutrients, 14(13), 2627. 7. Jovanovski, E., Mazhar, N., Komishon, A., Khayyat, R., Li, D., Mejía, S. B., Khan, T., Jenkins, A. L., Duvnjak, L., Sievenpiper, J. L., & Vuksan, V. (2020). Effect of viscous fiber supplementation on obesity indicators in individuals consuming calorie-restricted diets: a systematic review and meta-analysis of randomized controlled trials. European Journal of Nutrition (Print), 60(1), 101–112. 8. Namazi, N., Irandoost, P., Larijani, B., & Azadbakht, L. (2019). The effects of supplementation with conjugated linoleic acid on anthropometric indices and body composition in overweight and obese subjects: A systematic review and meta-analysis. Critical Reviews in Food Science and Nutrition, 59(17), 2720–2733. 9. Hamdallah, H., Elyse Ireland, H., & Williams, J. (2020). Conjugated Linoleic Acid (CLA) Effect on Body Weight and Body Composition in Women (Systematic Review and Meta-Analysis). Proceedings of the Nutrition Society, 79(OCE2), E262.



